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Upgrading to NetworkManager 1.10 broke use of network profiles for wired connections.
I use profiles to switch proxy settings via proxydriver and firewalld zones for the interface.
It was no longer possible to select a profile after the update.
It seems to be a simmilar problem like https://bbs.archlinux.org/viewtopic.php?id=231822
I deleted all connection Profiles for wired connections in /etc/NetworkManager/system-connections
and recreated them.
Now it works again.
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